TIM-1 Rabbit Polyclonal Antibody

TIM-1 Rabbit Polyclonal Antibody

To Order Contact Us Below:

    Anti-TIM 3/HAVCR2 Antibody
    A00657-1 100ug/vial
    EUR 352.8

    TIM-1 Antibody
    3809-002mg 0.02 mg
    EUR 206.18
    Description: TIM-1 Antibody: The human form of TIM-1 was initially discovered as a membrane glycoprotein through which the hepatitis A virus can gain entry into a cell. It was also identified as kidney injury molecule 1 (Kim-1), a predicted adhesion molecule that is upregulated on the surfaces of kidney epithelia. It is also expressed on T helper 2 (Th2) cells of the immune system, and following the binding of its natural ligand TIM-4, stimulates T cell expansion and cytokine production in response to viral challenge. It has been suggested that hyperactivation of TIM-1 leads to an increased level of Th2 responsiveness and asthma susceptibility, and antibodies to TIM-1 may therefore be a novel approach to treating asthma.

    TIM-1 Antibody
    3809-01mg 0.1 mg
    EUR 523.7
    Description: TIM-1 Antibody: The human form of TIM-1 was initially discovered as a membrane glycoprotein through which the hepatitis A virus can gain entry into a cell. It was also identified as kidney injury molecule 1 (Kim-1), a predicted adhesion molecule that is upregulated on the surfaces of kidney epithelia. It is also expressed on T helper 2 (Th2) cells of the immune system, and following the binding of its natural ligand TIM-4, stimulates T cell expansion and cytokine production in response to viral challenge. It has been suggested that hyperactivation of TIM-1 leads to an increased level of Th2 responsiveness and asthma susceptibility, and antibodies to TIM-1 may therefore be a novel approach to treating asthma.

    TIM-1 Antibody
    3811-002mg 0.02 mg
    EUR 206.18
    Description: TIM-1 Antibody: The human form of TIM-1 was initially discovered as a membrane glycoprotein through which the hepatitis A virus can gain entry into a cell. It was also identified as kidney injury molecule 1 (Kim-1), a predicted adhesion molecule that is upregulated on the surfaces of kidney epithelia. It is also expressed on T helper 2 (Th2) cells of the immune system, and following the binding of its natural ligand TIM-4, stimulates T cell expansion and cytokine production in response to viral challenge. It has been suggested that hyperactivation of TIM-1 leads to an increased level of Th2 responsiveness and asthma susceptibility, and antibodies to TIM-1 may therefore be a novel approach to treating asthma.

    TIM-1 Antibody
    3811-01mg 0.1 mg
    EUR 523.7
    Description: TIM-1 Antibody: The human form of TIM-1 was initially discovered as a membrane glycoprotein through which the hepatitis A virus can gain entry into a cell. It was also identified as kidney injury molecule 1 (Kim-1), a predicted adhesion molecule that is upregulated on the surfaces of kidney epithelia. It is also expressed on T helper 2 (Th2) cells of the immune system, and following the binding of its natural ligand TIM-4, stimulates T cell expansion and cytokine production in response to viral challenge. It has been suggested that hyperactivation of TIM-1 leads to an increased level of Th2 responsiveness and asthma susceptibility, and antibodies to TIM-1 may therefore be a novel approach to treating asthma.

    TIM-1 Antibody
    24416-100ul 100ul
    EUR 468

    TIM-1 Antibody
    24417-100ul 100ul
    EUR 468

    Anti-TIM-3 Antibody, PE-Labeled
    71121-1 50 µg
    EUR 355
    Description: R-Phycoerythrin-labeled recombinant human Anti-TIM-3 antibody recognizing the TIM3 binding region. This antibody has not been tested for cross-reactivity with any other species.

    TIM-1
    MO15036 100 ug
    EUR 710.4

    Oncogene TIM Polyclonal Antibody
    ES7597-100ul 100ul
    EUR 334.8
    Description: A Rabbit Polyclonal antibody against Oncogene TIM from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

    Oncogene TIM Polyclonal Antibody
    ES7597-50ul 50ul
    EUR 248.4
    Description: A Rabbit Polyclonal antibody against Oncogene TIM from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

    Oncogene TIM Polyclonal Antibody
    ABP56598-003ml 0.03ml
    EUR 189.6
    Description: A polyclonal antibody for detection of Oncogene TIM from Human, Mouse, Rat. This Oncogene TIM antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Oncogene TIM at AA range: 160-240

    Oncogene TIM Polyclonal Antibody
    ABP56598-01ml 0.1ml
    EUR 346.8
    Description: A polyclonal antibody for detection of Oncogene TIM from Human, Mouse, Rat. This Oncogene TIM antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Oncogene TIM at AA range: 160-240

    Oncogene TIM Polyclonal Antibody
    ABP56598-02ml 0.2ml
    EUR 496.8
    Description: A polyclonal antibody for detection of Oncogene TIM from Human, Mouse, Rat. This Oncogene TIM antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Oncogene TIM at AA range: 160-240

    Polyclonal TIM-4 Antibody
    APR06408G 0.1 mg
    EUR 790.8
    Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human TIM-4 . This antibody is tested and proven to work in the following applications:

    Polyclonal TIM-4 Antibody
    APR06409G 0.1 mg
    EUR 790.8
    Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human TIM-4 . This antibody is tested and proven to work in the following applications:

    Polyclonal Tim-3 Antibody
    APR00202G 0.1mg
    EUR 580.8
    Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Tim-3 . This antibody is tested and proven to work in the following applications:

    HRP-Goat Anti-Rabbit Secondary Antibody
    A12004
    • EUR 232.26
    • EUR 117.70
    • 350 µg
    • 350 ug

    Goat Anti-Rabbit Secondary Antibody, Biotin Conjugated
    A12001
    • EUR 232.26
    • EUR 117.70
    • 350 µg
    • 350 ug

    Anti-TIM-1 antibody
    STJ73133 100 µg
    EUR 430.8

    Anti-TIM-1 antibody
    STJ98725 200 µl
    EUR 236.4
    Description: Rabbit polyclonal to TIM-1.

    TIM antibody
    10R-10306 100 ug
    EUR 522
    Description: Mouse monoclonal TIM antibody

    TIM antibody
    10R-10307 100 ug
    EUR 522
    Description: Mouse monoclonal TIM antibody

    TIM-1 Antibody (KIM-1)
    R30715 100 ug
    EUR 419

    TIM-1 Peptide
    43-672P 0.1 mg
    EUR 405.6

    TIM-1 Peptide
    3809P 0.05 mg
    EUR 197.7
    Description: (NT) TIM-1 peptide

    TIM-1 Peptide
    3811P 0.05 mg
    EUR 197.7
    Description: (IN) TIM-1 peptide

    anti-TIM 1
    YF-PA18329 50 ug
    EUR 435.6
    Description: Mouse polyclonal to TIM 1

    anti-TIM 1
    YF-PA18330 100 ug
    EUR 483.6
    Description: Rabbit polyclonal to TIM 1

    anti-TIM 1
    YF-PA26016 50 ul
    EUR 400.8
    Description: Mouse polyclonal to TIM 1

    Anti-TIM 1/HAVCR1 Antibody
    A01306 100ug/vial
    EUR 352.8

    Anti-TIM 1/HAVCR1 Antibody
    PA1624 100ug/vial
    EUR 400.8

    Anti-TIM 1/HAVCR1 Antibody
    PA1632 100ug/vial
    EUR 400.8

    Anti-TIM 1/HAVCR1 Antibody
    RP1093 100ug/vial
    EUR 352.8

    Polyclonal Goat Anti-TIM-1 Antibody (internal region)
    APR11107G 0.1mg
    EUR 580.8
    Description: A polyclonal antibody raised in Goat that recognizes and binds to Human Goat Anti-TIM-1 (internal region). This antibody is tested and proven to work in the following applications:

    Human Triosephosphate Isomerase (TIM) AssayMax ELISA Kit
    ET3025-1 96 Well Plate
    EUR 500.4

    TIM-3, Avi-Tag, Biotin Labeled (Human)
    79096-1 25 µg
    EUR 295
    Description: Human TIM-3, also known as T-cell immunoglobulin mucin receptor 3, T-cell membrane protein 3, TIMD-3, Hepatitis A virus cellular receptor 2, HAVCR-2, and KIM-3. GenBank Accession No. NM_032782, a.a. 24-130 with a C-terminal Avi-tag, expressed in an E. coli cell expression system and enzymatically biotin-labeled using AviTag™ technology. MW = 14 kDa.

    KIM-1 Antibody / TIM-1 / HAVCR1
    R32305 100 ug
    EUR 419

    KIM-1 Antibody / TIM-1 / HAVCR1
    RQ4572 100ug
    EUR 419

    TIM 4 Antibody
    DF13636 100ul
    EUR 420

    TIM-4 Antibody
    3813-002mg 0.02 mg
    EUR 206.18
    Description: TIM-4 Antibody: The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors that are involved in the regulation of T helper (Th) -1 and -2 cell-mediated immunity. TIM-4, which is preferentially expressed on macrophages and dendritic cells, is the natural ligand of TIM-1, and this binding leads to T-cell expansion and cytokine production. Unlike other members of the TIM family, TIM-4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain. The TIM-4 gene maps to a locus associated with predisposition to asthma in both mice and humans and with its connection to TIM-1-triggered Th2 responsiveness, may be considered as a candidate disease/predisposition gene for asthma.

    TIM-4 Antibody
    3813-01mg 0.1 mg
    EUR 523.7
    Description: TIM-4 Antibody: The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors that are involved in the regulation of T helper (Th) -1 and -2 cell-mediated immunity. TIM-4, which is preferentially expressed on macrophages and dendritic cells, is the natural ligand of TIM-1, and this binding leads to T-cell expansion and cytokine production. Unlike other members of the TIM family, TIM-4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain. The TIM-4 gene maps to a locus associated with predisposition to asthma in both mice and humans and with its connection to TIM-1-triggered Th2 responsiveness, may be considered as a candidate disease/predisposition gene for asthma.

    TIM-4 Antibody
    3815-002mg 0.02 mg
    EUR 206.18
    Description: TIM-4 Antibody: The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors that are involved in the regulation of T helper (Th) -1 and -2 cell-mediated immunity. TIM-4, which is preferentially expressed on macrophages and dendritic cells, is the natural ligand of TIM-1, and this binding leads to T-cell expansion and cytokine production. Unlike other members of the TIM family, TIM-4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain. The TIM-4 gene maps to a locus associated with predisposition to asthma in both mice and humans and with its connection to TIM-1-triggered Th2 responsiveness, may be considered as a candidate disease/predisposition gene for asthma.

    TIM-4 Antibody
    3815-01mg 0.1 mg
    EUR 523.7
    Description: TIM-4 Antibody: The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors that are involved in the regulation of T helper (Th) -1 and -2 cell-mediated immunity. TIM-4, which is preferentially expressed on macrophages and dendritic cells, is the natural ligand of TIM-1, and this binding leads to T-cell expansion and cytokine production. Unlike other members of the TIM family, TIM-4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain. The TIM-4 gene maps to a locus associated with predisposition to asthma in both mice and humans and with its connection to TIM-1-triggered Th2 responsiveness, may be considered as a candidate disease/predisposition gene for asthma.

    TIM-4 Antibody
    24418-100ul 100ul
    EUR 468

    TIM-4 Antibody
    24419-100ul 100ul
    EUR 468

    TIM-3 Antibody
    8659-002mg 0.02 mg
    EUR 206.18
    Description: The immune checkpoint protein TIM-3 is a member of the immunoglobulin superfamily and TIM family of proteins that was initially identified as a specific marker of fully differentiated IFN-γ producing CD4 T helper 1 (Th1) and CD8 cytotoxic cells. It is a Th1-specific cell surface protein that regulates macrophage activation and negatively regulates Th1-mediated auto- and alloimmune responses, and is also highly expressed on regulatory T cells, monocytes, macrophages, and dendritic cells (1). TIM-3 and PD-1 are co-expressed on most CD4 and CD8 T cells infiltrating solid tumors or in hematologic malignancy in mice; blocking TIM-3 in conjugation with a PD-1 blockade increases the functionality of exhausted T cells and synergizes with to inhibit tumor growth (2,3).

    TIM-3 Antibody
    8659-01mg 0.1 mg
    EUR 523.7
    Description: The immune checkpoint protein TIM-3 is a member of the immunoglobulin superfamily and TIM family of proteins that was initially identified as a specific marker of fully differentiated IFN-γ producing CD4 T helper 1 (Th1) and CD8 cytotoxic cells. It is a Th1-specific cell surface protein that regulates macrophage activation and negatively regulates Th1-mediated auto- and alloimmune responses, and is also highly expressed on regulatory T cells, monocytes, macrophages, and dendritic cells (1). TIM-3 and PD-1 are co-expressed on most CD4 and CD8 T cells infiltrating solid tumors or in hematologic malignancy in mice; blocking TIM-3 in conjugation with a PD-1 blockade increases the functionality of exhausted T cells and synergizes with to inhibit tumor growth (2,3).

    TIM-3 Antibody
    R34699-100UG 100 ug
    EUR 399

    Tim-3 Antibody
    3808-100 each
    EUR 379.2

    Tim-3 Antibody
    3808-30T each
    EUR 175.2

    Tim-1 Recombinant Protein
    90-546 100 ug
    EUR 752.1
    Description: The TIM (T cell/transmembrane, immunoglobulin and mucin) family plays a critical role in regulating immune responses, including allergy, asthma, transplant tolerance, autoimmunity and the response to viral infections. The unique structure of TIM immunoglobulin variable region domains allows highly specific recognition of phosphatidylserine (PtdSer), exposed on the surface of apoptotic cells. TIM-1 (T cell-immunoglobulinmucin; also KIM-1 and HAVcr-1) is a 100 kDa, type I transmembrane glycoprotein member of the TIM family of immunoglobulin superfamily molecules. There are two cytoplasmic alternate splice forms of TIM1. One is a long (359 aa) kidney form termed TIM-1b, and one is a short (334 aa) liver form termed TIM-1a. TIM-1, important for asthma and allergy, is preferentially expressed on T-helper 2 (Th2) cells and functions as a potent costimulatory molecule for T cell activation.

    Tim-1 Recombinant Protein
    90-547 100 ug
    EUR 752.1
    Description: The TIM (T cell/transmembrane, immunoglobulin and mucin) family plays a critical role in regulating immune responses, including allergy, asthma, transplant tolerance, autoimmunity and the response to viral infections. The unique structure of TIM immunoglobulin variable region domains allows highly specific recognition of phosphatidylserine (PtdSer), exposed on the surface of apoptotic cells. Tim-1 (KIM-1; HAVcr-1) is a 100 kDa, type I transmembrane glycoprotein member of the TIM family of immunoglobulin superfamily molecules. There are two cytoplasmic alternate splice forms of Tim-1. One is a long (359 aa) kidney form termed Tim-1b, and one is a short (334 aa) liver form termed Tim-1a. Tim-1, important for asthma and allergy, is preferentially expressed on T-helper 2 (Th2) cells and functions as a potent costimulatory molecule for T cell activation.

    Anti-TIM 1 (2G11)
    YF-MA18139 100 ug
    EUR 435.6
    Description: Mouse monoclonal to TIM 1

    Anti-TIM 1 (1E5)
    YF-MA11444 100 ug
    EUR 435.6
    Description: Mouse monoclonal to TIM 1

    Anti-TIM 1 (2B9)
    YF-MA11445 100 ug
    EUR 435.6
    Description: Mouse monoclonal to TIM 1

    Tim-1, Human Recombinant
    P1351-10 each
    EUR 196.8

    Tim-1, Human Recombinant
    P1351-50 each
    EUR 627.6

    Tim-1, Mouse Recombinant
    P1354-10 each
    EUR 196.8

    Tim-1, Mouse Recombinant
    P1354-50 each
    EUR 627.6

    Goat Anti Human Tim-3 Polyclonal Antibody
    CPBT-65285GH 0.1 mg
    EUR 1008

    Polyclonal TIMD4 / TIM4 / TIM-4 Antibody (Internal)
    APR02384G 0.05mg
    EUR 580.8
    Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human TIMD4 / TIM4 / TIM-4 (Internal). This antibody is tested and proven to work in the following applications:

    Polyclonal HAVCR2 / TIM-3 Antibody (aa176-194)
    APR03015G 0.05ml
    EUR 580.8
    Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human HAVCR2 / TIM-3 (aa176-194). This antibody is tested and proven to work in the following applications:

    Triosephosphate Isomerase (TIM) Antibody
    20-abx141692
    • EUR 444.00
    • EUR 727.20
    • EUR 360.00
    • 100 ul
    • 200 ul
    • 50 ul

    Triosephosphate Isomerase (TIM) Antibody
    20-abx018098
    • EUR 460.80
    • EUR 126.00
    • 100 ug
    • 20 ug

    Triosephosphate Isomerase (TIM) Antibody
    abx018099-100ug 100 ug
    EUR 460.8

    Anti-Oncogene TIM antibody
    STJ94826 200 µl
    EUR 236.4
    Description: Rabbit polyclonal to Oncogene TIM.

    TIM-3 Antibody / HAVCR2
    RQ4354 100 ug
    EUR 419

    TIM-3 Antibody / HAVCR2
    V8495-100UG 100 ug
    EUR 499
    Description: TIMs are type I transmembrane glycoproteins with one Ig-like V-type domain and a Ser/Thr-rich mucin stalk. TIM-3 is expressed on the surface of effector T cel tonsil, lymph node or spleen. ls (CD4+Th1 and CD8+Tc1) but not on helper T cells (CD4+Th2 and CD8+Tc2). In chronic inflammation, autoimmune disorders, and some cancers, TIM-3 is upregulated on several other hematopoietic cell types. The Ig domain of TIM-3 interacts with a ligand on resting but not activated Th1 and Th2 cells. The glycosylated Ig domain of TIM-3 binds cell-associated galectin-9. This induces TIM-3 Tyr phosphorylation and pro-apoptotic signaling. TIM-3 functions as a negative regulator of Th1 cell activity. Its blockade results in increased IFN-gamma production, Th1 cell proliferation and cytotoxicity, regulatory T cell development, and increases in macrophage and neutrophil infiltration into sites of inflammation.

    TIM-3 Antibody / HAVCR2
    V8495-20UG 20 ug
    EUR 219
    Description: TIMs are type I transmembrane glycoproteins with one Ig-like V-type domain and a Ser/Thr-rich mucin stalk. TIM-3 is expressed on the surface of effector T cel tonsil, lymph node or spleen. ls (CD4+Th1 and CD8+Tc1) but not on helper T cells (CD4+Th2 and CD8+Tc2). In chronic inflammation, autoimmune disorders, and some cancers, TIM-3 is upregulated on several other hematopoietic cell types. The Ig domain of TIM-3 interacts with a ligand on resting but not activated Th1 and Th2 cells. The glycosylated Ig domain of TIM-3 binds cell-associated galectin-9. This induces TIM-3 Tyr phosphorylation and pro-apoptotic signaling. TIM-3 functions as a negative regulator of Th1 cell activity. Its blockade results in increased IFN-gamma production, Th1 cell proliferation and cytotoxicity, regulatory T cell development, and increases in macrophage and neutrophil infiltration into sites of inflammation.

    TIM-3 Antibody / HAVCR2
    V8495SAF-100UG 100 ug
    EUR 499
    Description: TIMs are type I transmembrane glycoproteins with one Ig-like V-type domain and a Ser/Thr-rich mucin stalk. TIM-3 is expressed on the surface of effector T cel tonsil, lymph node or spleen. ls (CD4+Th1 and CD8+Tc1) but not on helper T cells (CD4+Th2 and CD8+Tc2). In chronic inflammation, autoimmune disorders, and some cancers, TIM-3 is upregulated on several other hematopoietic cell types. The Ig domain of TIM-3 interacts with a ligand on resting but not activated Th1 and Th2 cells. The glycosylated Ig domain of TIM-3 binds cell-associated galectin-9. This induces TIM-3 Tyr phosphorylation and pro-apoptotic signaling. TIM-3 functions as a negative regulator of Th1 cell activity. Its blockade results in increased IFN-gamma production, Th1 cell proliferation and cytotoxicity, regulatory T cell development, and increases in macrophage and neutrophil infiltration into sites of inflammation.

    TIM-3 Antibody / HAVCR2
    V7533-100UG 100 ug
    EUR 499
    Description: The protein encoded by the HAVCR2 gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [RefSeq]

    TIM-3 Antibody / HAVCR2
    V7533-20UG 20 ug
    EUR 219
    Description: The protein encoded by the HAVCR2 gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [RefSeq]

    TIM-3 Antibody / HAVCR2
    V7533IHC-7ML 7 ml
    EUR 499
    Description: The protein encoded by the HAVCR2 gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [RefSeq]

    TIM-3 Antibody / HAVCR2
    V7533SAF-100UG 100 ug
    EUR 499
    Description: The protein encoded by the HAVCR2 gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [RefSeq]

    TIM-3 Antibody / HAVCR2
    V7582-100UG 100 ug
    EUR 499
    Description: TIMs are type I transmembrane glycoproteins with one Ig-like V-type domain and a Ser/Thr-rich mucin stalk. TIM-3 is expressed on the surface of effector T cells (CD4+Th1 and CD8+Tc1) but not on helper T cells (CD4+Th2 and CD8+Tc2). In chronic inflammation, autoimmune disorders, and some cancers, TIM-3 is upregulated on several other hematopoietic cell types. The Ig domain of TIM-3 interacts with a ligand on resting but not activated Th1 and Th2 cells. The glycosylated Ig domain of TIM-3 binds cell-associated galectin-9. This induces TIM-3 Tyr phosphorylation and pro-apoptotic signaling. TIM-3 functions as a negative regulator of Th1 cell activity. Its blockade results in increased IFN-gamma production, Th1 cell proliferation and cytotoxicity, regulatory T cell development, and increases in macrophage and neutrophil infiltration into sites of inflammation.

    TIM-3 Antibody / HAVCR2
    V7582-20UG 20 ug
    EUR 219
    Description: TIMs are type I transmembrane glycoproteins with one Ig-like V-type domain and a Ser/Thr-rich mucin stalk. TIM-3 is expressed on the surface of effector T cells (CD4+Th1 and CD8+Tc1) but not on helper T cells (CD4+Th2 and CD8+Tc2). In chronic inflammation, autoimmune disorders, and some cancers, TIM-3 is upregulated on several other hematopoietic cell types. The Ig domain of TIM-3 interacts with a ligand on resting but not activated Th1 and Th2 cells. The glycosylated Ig domain of TIM-3 binds cell-associated galectin-9. This induces TIM-3 Tyr phosphorylation and pro-apoptotic signaling. TIM-3 functions as a negative regulator of Th1 cell activity. Its blockade results in increased IFN-gamma production, Th1 cell proliferation and cytotoxicity, regulatory T cell development, and increases in macrophage and neutrophil infiltration into sites of inflammation.

    TIM-3 Antibody / HAVCR2
    V7582IHC-7ML 7 ml
    EUR 499
    Description: TIMs are type I transmembrane glycoproteins with one Ig-like V-type domain and a Ser/Thr-rich mucin stalk. TIM-3 is expressed on the surface of effector T cells (CD4+Th1 and CD8+Tc1) but not on helper T cells (CD4+Th2 and CD8+Tc2). In chronic inflammation, autoimmune disorders, and some cancers, TIM-3 is upregulated on several other hematopoietic cell types. The Ig domain of TIM-3 interacts with a ligand on resting but not activated Th1 and Th2 cells. The glycosylated Ig domain of TIM-3 binds cell-associated galectin-9. This induces TIM-3 Tyr phosphorylation and pro-apoptotic signaling. TIM-3 functions as a negative regulator of Th1 cell activity. Its blockade results in increased IFN-gamma production, Th1 cell proliferation and cytotoxicity, regulatory T cell development, and increases in macrophage and neutrophil infiltration into sites of inflammation.

    TIM-3 Antibody / HAVCR2
    V7582SAF-100UG 100 ug
    EUR 499
    Description: TIMs are type I transmembrane glycoproteins with one Ig-like V-type domain and a Ser/Thr-rich mucin stalk. TIM-3 is expressed on the surface of effector T cells (CD4+Th1 and CD8+Tc1) but not on helper T cells (CD4+Th2 and CD8+Tc2). In chronic inflammation, autoimmune disorders, and some cancers, TIM-3 is upregulated on several other hematopoietic cell types. The Ig domain of TIM-3 interacts with a ligand on resting but not activated Th1 and Th2 cells. The glycosylated Ig domain of TIM-3 binds cell-associated galectin-9. This induces TIM-3 Tyr phosphorylation and pro-apoptotic signaling. TIM-3 functions as a negative regulator of Th1 cell activity. Its blockade results in increased IFN-gamma production, Th1 cell proliferation and cytotoxicity, regulatory T cell development, and increases in macrophage and neutrophil infiltration into sites of inflammation.

    TIM-3 Antibody / HAVCR2
    V8724-100UG 100 ug
    EUR 499
    Description: TIMs are type I transmembrane glycoproteins with one Ig-like V-type domain and a Ser/Thr-rich mucin stalk. TIM-3 is expressed on the surface of effector T cel tonsil, lymph node or spleen. ls (CD4+Th1 and CD8+Tc1) but not on helper T cells (CD4+Th2 and CD8+Tc2). In chronic inflammation, autoimmune disorders, and some cancers, TIM-3 is upregulated on several other hematopoietic cell types. The Ig domain of TIM-3 interacts with a ligand on resting but not activated Th1 and Th2 cells. The glycosylated Ig domain of TIM-3 binds cell-associated galectin-9. This induces TIM-3 Tyr phosphorylation and pro-apoptotic signaling. TIM-3 functions as a negative regulator of Th1 cell activity. Its blockade results in increased IFN-gamma production, Th1 cell proliferation and cytotoxicity, regulatory T cell development, and increases in macrophage and neutrophil infiltration into sites of inflammation.

    TIM-3 Antibody / HAVCR2
    V8724-20UG 20 ug
    EUR 219
    Description: TIMs are type I transmembrane glycoproteins with one Ig-like V-type domain and a Ser/Thr-rich mucin stalk. TIM-3 is expressed on the surface of effector T cel tonsil, lymph node or spleen. ls (CD4+Th1 and CD8+Tc1) but not on helper T cells (CD4+Th2 and CD8+Tc2). In chronic inflammation, autoimmune disorders, and some cancers, TIM-3 is upregulated on several other hematopoietic cell types. The Ig domain of TIM-3 interacts with a ligand on resting but not activated Th1 and Th2 cells. The glycosylated Ig domain of TIM-3 binds cell-associated galectin-9. This induces TIM-3 Tyr phosphorylation and pro-apoptotic signaling. TIM-3 functions as a negative regulator of Th1 cell activity. Its blockade results in increased IFN-gamma production, Th1 cell proliferation and cytotoxicity, regulatory T cell development, and increases in macrophage and neutrophil infiltration into sites of inflammation.

    TIM-3 Antibody / HAVCR2
    V8724SAF-100UG 100 ug
    EUR 499
    Description: TIMs are type I transmembrane glycoproteins with one Ig-like V-type domain and a Ser/Thr-rich mucin stalk. TIM-3 is expressed on the surface of effector T cel tonsil, lymph node or spleen. ls (CD4+Th1 and CD8+Tc1) but not on helper T cells (CD4+Th2 and CD8+Tc2). In chronic inflammation, autoimmune disorders, and some cancers, TIM-3 is upregulated on several other hematopoietic cell types. The Ig domain of TIM-3 interacts with a ligand on resting but not activated Th1 and Th2 cells. The glycosylated Ig domain of TIM-3 binds cell-associated galectin-9. This induces TIM-3 Tyr phosphorylation and pro-apoptotic signaling. TIM-3 functions as a negative regulator of Th1 cell activity. Its blockade results in increased IFN-gamma production, Th1 cell proliferation and cytotoxicity, regulatory T cell development, and increases in macrophage and neutrophil infiltration into sites of inflammation.

    TIM-3 Antibody / HAVCR2
    V8753-100UG 100 ug
    EUR 499
    Description: TIMs are type I transmembrane glycoproteins with one Ig-like V-type domain and a Ser/Thr-rich mucin stalk. TIM-3 is expressed on the surface of effector T cel tonsil, lymph node or spleen. ls (CD4+Th1 and CD8+Tc1) but not on helper T cells (CD4+Th2 and CD8+Tc2). In chronic inflammation, autoimmune disorders, and some cancers, TIM-3 is upregulated on several other hematopoietic cell types. The Ig domain of TIM-3 interacts with a ligand on resting but not activated Th1 and Th2 cells. The glycosylated Ig domain of TIM-3 binds cell-associated galectin-9. This induces TIM-3 Tyr phosphorylation and pro-apoptotic signaling. TIM-3 functions as a negative regulator of Th1 cell activity. Its blockade results in increased IFN-gamma production, Th1 cell proliferation and cytotoxicity, regulatory T cell development, and increases in macrophage and neutrophil infiltration into sites of inflammation.

    TIM-3 Antibody / HAVCR2
    V8753-20UG 20 ug
    EUR 219
    Description: TIMs are type I transmembrane glycoproteins with one Ig-like V-type domain and a Ser/Thr-rich mucin stalk. TIM-3 is expressed on the surface of effector T cel tonsil, lymph node or spleen. ls (CD4+Th1 and CD8+Tc1) but not on helper T cells (CD4+Th2 and CD8+Tc2). In chronic inflammation, autoimmune disorders, and some cancers, TIM-3 is upregulated on several other hematopoietic cell types. The Ig domain of TIM-3 interacts with a ligand on resting but not activated Th1 and Th2 cells. The glycosylated Ig domain of TIM-3 binds cell-associated galectin-9. This induces TIM-3 Tyr phosphorylation and pro-apoptotic signaling. TIM-3 functions as a negative regulator of Th1 cell activity. Its blockade results in increased IFN-gamma production, Th1 cell proliferation and cytotoxicity, regulatory T cell development, and increases in macrophage and neutrophil infiltration into sites of inflammation.

    TIM-3 Antibody / HAVCR2
    V8753SAF-100UG 100 ug
    EUR 499
    Description: TIMs are type I transmembrane glycoproteins with one Ig-like V-type domain and a Ser/Thr-rich mucin stalk. TIM-3 is expressed on the surface of effector T cel tonsil, lymph node or spleen. ls (CD4+Th1 and CD8+Tc1) but not on helper T cells (CD4+Th2 and CD8+Tc2). In chronic inflammation, autoimmune disorders, and some cancers, TIM-3 is upregulated on several other hematopoietic cell types. The Ig domain of TIM-3 interacts with a ligand on resting but not activated Th1 and Th2 cells. The glycosylated Ig domain of TIM-3 binds cell-associated galectin-9. This induces TIM-3 Tyr phosphorylation and pro-apoptotic signaling. TIM-3 functions as a negative regulator of Th1 cell activity. Its blockade results in increased IFN-gamma production, Th1 cell proliferation and cytotoxicity, regulatory T cell development, and increases in macrophage and neutrophil infiltration into sites of inflammation.

    TIM-3 Antibody / HAVCR2
    V8754-100UG 100 ug
    EUR 499
    Description: TIMs are type I transmembrane glycoproteins with one Ig-like V-type domain and a Ser/Thr-rich mucin stalk. TIM-3 is expressed on the surface of effector T cel tonsil, lymph node or spleen. ls (CD4+Th1 and CD8+Tc1) but not on helper T cells (CD4+Th2 and CD8+Tc2). In chronic inflammation, autoimmune disorders, and some cancers, TIM-3 is upregulated on several other hematopoietic cell types. The Ig domain of TIM-3 interacts with a ligand on resting but not activated Th1 and Th2 cells. The glycosylated Ig domain of TIM-3 binds cell-associated galectin-9. This induces TIM-3 Tyr phosphorylation and pro-apoptotic signaling. TIM-3 functions as a negative regulator of Th1 cell activity. Its blockade results in increased IFN-gamma production, Th1 cell proliferation and cytotoxicity, regulatory T cell development, and increases in macrophage and neutrophil infiltration into sites of inflammation.

    TIM-3 Antibody / HAVCR2
    V8754-20UG 20 ug
    EUR 219
    Description: TIMs are type I transmembrane glycoproteins with one Ig-like V-type domain and a Ser/Thr-rich mucin stalk. TIM-3 is expressed on the surface of effector T cel tonsil, lymph node or spleen. ls (CD4+Th1 and CD8+Tc1) but not on helper T cells (CD4+Th2 and CD8+Tc2). In chronic inflammation, autoimmune disorders, and some cancers, TIM-3 is upregulated on several other hematopoietic cell types. The Ig domain of TIM-3 interacts with a ligand on resting but not activated Th1 and Th2 cells. The glycosylated Ig domain of TIM-3 binds cell-associated galectin-9. This induces TIM-3 Tyr phosphorylation and pro-apoptotic signaling. TIM-3 functions as a negative regulator of Th1 cell activity. Its blockade results in increased IFN-gamma production, Th1 cell proliferation and cytotoxicity, regulatory T cell development, and increases in macrophage and neutrophil infiltration into sites of inflammation.

    TIM-3 Antibody / HAVCR2
    V8754SAF-100UG 100 ug
    EUR 499
    Description: TIMs are type I transmembrane glycoproteins with one Ig-like V-type domain and a Ser/Thr-rich mucin stalk. TIM-3 is expressed on the surface of effector T cel tonsil, lymph node or spleen. ls (CD4+Th1 and CD8+Tc1) but not on helper T cells (CD4+Th2 and CD8+Tc2). In chronic inflammation, autoimmune disorders, and some cancers, TIM-3 is upregulated on several other hematopoietic cell types. The Ig domain of TIM-3 interacts with a ligand on resting but not activated Th1 and Th2 cells. The glycosylated Ig domain of TIM-3 binds cell-associated galectin-9. This induces TIM-3 Tyr phosphorylation and pro-apoptotic signaling. TIM-3 functions as a negative regulator of Th1 cell activity. Its blockade results in increased IFN-gamma production, Th1 cell proliferation and cytotoxicity, regulatory T cell development, and increases in macrophage and neutrophil infiltration into sites of inflammation.

    TIM-3 Antibody / HAVCR2
    V8755-100UG 100 ug
    EUR 499
    Description: TIMs are type I transmembrane glycoproteins with one Ig-like V-type domain and a Ser/Thr-rich mucin stalk. TIM-3 is expressed on the surface of effector T cel tonsil, lymph node or spleen. ls (CD4+Th1 and CD8+Tc1) but not on helper T cells (CD4+Th2 and CD8+Tc2). In chronic inflammation, autoimmune disorders, and some cancers, TIM-3 is upregulated on several other hematopoietic cell types. The Ig domain of TIM-3 interacts with a ligand on resting but not activated Th1 and Th2 cells. The glycosylated Ig domain of TIM-3 binds cell-associated galectin-9. This induces TIM-3 Tyr phosphorylation and pro-apoptotic signaling. TIM-3 functions as a negative regulator of Th1 cell activity. Its blockade results in increased IFN-gamma production, Th1 cell proliferation and cytotoxicity, regulatory T cell development, and increases in macrophage and neutrophil infiltration into sites of inflammation.

    TIM-3 Antibody / HAVCR2
    V8755-20UG 20 ug
    EUR 219
    Description: TIMs are type I transmembrane glycoproteins with one Ig-like V-type domain and a Ser/Thr-rich mucin stalk. TIM-3 is expressed on the surface of effector T cel tonsil, lymph node or spleen. ls (CD4+Th1 and CD8+Tc1) but not on helper T cells (CD4+Th2 and CD8+Tc2). In chronic inflammation, autoimmune disorders, and some cancers, TIM-3 is upregulated on several other hematopoietic cell types. The Ig domain of TIM-3 interacts with a ligand on resting but not activated Th1 and Th2 cells. The glycosylated Ig domain of TIM-3 binds cell-associated galectin-9. This induces TIM-3 Tyr phosphorylation and pro-apoptotic signaling. TIM-3 functions as a negative regulator of Th1 cell activity. Its blockade results in increased IFN-gamma production, Th1 cell proliferation and cytotoxicity, regulatory T cell development, and increases in macrophage and neutrophil infiltration into sites of inflammation.

    TIM-3 Antibody / HAVCR2
    V8755SAF-100UG 100 ug
    EUR 499
    Description: TIMs are type I transmembrane glycoproteins with one Ig-like V-type domain and a Ser/Thr-rich mucin stalk. TIM-3 is expressed on the surface of effector T cel tonsil, lymph node or spleen. ls (CD4+Th1 and CD8+Tc1) but not on helper T cells (CD4+Th2 and CD8+Tc2). In chronic inflammation, autoimmune disorders, and some cancers, TIM-3 is upregulated on several other hematopoietic cell types. The Ig domain of TIM-3 interacts with a ligand on resting but not activated Th1 and Th2 cells. The glycosylated Ig domain of TIM-3 binds cell-associated galectin-9. This induces TIM-3 Tyr phosphorylation and pro-apoptotic signaling. TIM-3 functions as a negative regulator of Th1 cell activity. Its blockade results in increased IFN-gamma production, Th1 cell proliferation and cytotoxicity, regulatory T cell development, and increases in macrophage and neutrophil infiltration into sites of inflammation.

    TIM-3 Antibody / HAVCR2
    V8766-100UG 100 ug
    EUR 499
    Description: TIMs are type I transmembrane glycoproteins with one Ig-like V-type domain and a Ser/Thr-rich mucin stalk. TIM-3 is expressed on the surface of effector T cells (CD4+ Th1 and CD8+Tc1) but not on helper T cells (CD4+Th2 and CD8+Tc2). In chronic inflammation, autoimmune disorders, and some cancers, TIM-3 is upregulated on several other hematopoietic cell types. The Ig domain of TIM-3 interacts with a ligand on resting but not activated Th1 and Th2 cells. The glycosylated Ig domain of TIM-3 binds cell-associated galectin-9. This induces TIM-3 Tyr phosphorylation and pro-apoptotic signaling. TIM-3 functions as a negative regulator of Th1 cell activity. Its blockade results in increased IFN-gamma production, Th1 cell proliferation and cytotoxicity, regulatory T cell development, and increases in macrophage and neutrophil infiltration into sites of inflammation.

    TIM-3 Antibody / HAVCR2
    V8766-20UG 20 ug
    EUR 219
    Description: TIMs are type I transmembrane glycoproteins with one Ig-like V-type domain and a Ser/Thr-rich mucin stalk. TIM-3 is expressed on the surface of effector T cells (CD4+ Th1 and CD8+Tc1) but not on helper T cells (CD4+Th2 and CD8+Tc2). In chronic inflammation, autoimmune disorders, and some cancers, TIM-3 is upregulated on several other hematopoietic cell types. The Ig domain of TIM-3 interacts with a ligand on resting but not activated Th1 and Th2 cells. The glycosylated Ig domain of TIM-3 binds cell-associated galectin-9. This induces TIM-3 Tyr phosphorylation and pro-apoptotic signaling. TIM-3 functions as a negative regulator of Th1 cell activity. Its blockade results in increased IFN-gamma production, Th1 cell proliferation and cytotoxicity, regulatory T cell development, and increases in macrophage and neutrophil infiltration into sites of inflammation.

    TIM-3 Antibody / HAVCR2
    V8766SAF-100UG 100 ug
    EUR 499
    Description: TIMs are type I transmembrane glycoproteins with one Ig-like V-type domain and a Ser/Thr-rich mucin stalk. TIM-3 is expressed on the surface of effector T cells (CD4+ Th1 and CD8+Tc1) but not on helper T cells (CD4+Th2 and CD8+Tc2). In chronic inflammation, autoimmune disorders, and some cancers, TIM-3 is upregulated on several other hematopoietic cell types. The Ig domain of TIM-3 interacts with a ligand on resting but not activated Th1 and Th2 cells. The glycosylated Ig domain of TIM-3 binds cell-associated galectin-9. This induces TIM-3 Tyr phosphorylation and pro-apoptotic signaling. TIM-3 functions as a negative regulator of Th1 cell activity. Its blockade results in increased IFN-gamma production, Th1 cell proliferation and cytotoxicity, regulatory T cell development, and increases in macrophage and neutrophil infiltration into sites of inflammation.

    TIM-3 Antibody / HAVCR2
    V9177-100UG 100ug
    EUR 499
    Description: TIMs are type I transmembrane glycoproteins with one Ig-like V-type domain and a Ser/Thr-rich mucin stalk. TIM-3 is expressed on the surface of effector T cell tonsil, lymph node or spleen. ls (CD4+Th1 and CD8+Tc1) but not on helper T cells (CD4+Th2 and CD8+Tc2). In chronic inflammation, autoimmune disorders, and some cancers, TIM-3 is upregulated on several other hematopoietic cell types. The Ig domain of TIM-3 interacts with a ligand on resting but not activated Th1 and Th2 cells. The glycosylated Ig domain of TIM-3 binds cell-associated galectin-9. This induces TIM-3 Tyr phosphorylation and pro-apoptotic signaling. TIM-3 functions as a negative regulator of Th1 cell activity. Its blockade results in increased IFN-gamma production, Th1 cell proliferation and cytotoxicity, regulatory T cell development, and increases in macrophage and neutrophil infiltration into sites of inflammation.

    TIM-3 Antibody / HAVCR2
    V9177-20UG 20ug
    EUR 219
    Description: TIMs are type I transmembrane glycoproteins with one Ig-like V-type domain and a Ser/Thr-rich mucin stalk. TIM-3 is expressed on the surface of effector T cell tonsil, lymph node or spleen. ls (CD4+Th1 and CD8+Tc1) but not on helper T cells (CD4+Th2 and CD8+Tc2). In chronic inflammation, autoimmune disorders, and some cancers, TIM-3 is upregulated on several other hematopoietic cell types. The Ig domain of TIM-3 interacts with a ligand on resting but not activated Th1 and Th2 cells. The glycosylated Ig domain of TIM-3 binds cell-associated galectin-9. This induces TIM-3 Tyr phosphorylation and pro-apoptotic signaling. TIM-3 functions as a negative regulator of Th1 cell activity. Its blockade results in increased IFN-gamma production, Th1 cell proliferation and cytotoxicity, regulatory T cell development, and increases in macrophage and neutrophil infiltration into sites of inflammation.

    TIM-3 Antibody / HAVCR2
    V9177SAF-100UG 100ug
    EUR 499
    Description: TIMs are type I transmembrane glycoproteins with one Ig-like V-type domain and a Ser/Thr-rich mucin stalk. TIM-3 is expressed on the surface of effector T cell tonsil, lymph node or spleen. ls (CD4+Th1 and CD8+Tc1) but not on helper T cells (CD4+Th2 and CD8+Tc2). In chronic inflammation, autoimmune disorders, and some cancers, TIM-3 is upregulated on several other hematopoietic cell types. The Ig domain of TIM-3 interacts with a ligand on resting but not activated Th1 and Th2 cells. The glycosylated Ig domain of TIM-3 binds cell-associated galectin-9. This induces TIM-3 Tyr phosphorylation and pro-apoptotic signaling. TIM-3 functions as a negative regulator of Th1 cell activity. Its blockade results in increased IFN-gamma production, Th1 cell proliferation and cytotoxicity, regulatory T cell development, and increases in macrophage and neutrophil infiltration into sites of inflammation.

    TIM-1, Avi-His-Tag
    72512 100 µg
    EUR 320
    Description: Human TIM-1, also known as T-cell immunoglobulin, Hepatitis A virus cellular receptor 1, and HAVCR1, with a C-terminal Avi-His-Tag. GenBank Accession No. NM_012206, a.a. 21-293, expressed in a HEK293 cell expression system. MW = 32 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.

    Rabbit Polyclonal Antibody to Human Topoisomerase IIα
    TG2011-1 250 units
    EUR 496.8

    Polyclonal Rabbit anti-sEH
    SEH-1 50 uL
    EUR 336

    Anti-Sumo 1 Rabbit Monoclonal Antibody
    M00631-1 100ug/vial
    EUR 476.4
    Description: Rabbit Monoclonal Sumo 1 Antibody. Validated in IP, IF, IHC, WB and tested in Human, Mouse, Rat.

    Anti-Cytokeratin 1 Rabbit Monoclonal Antibody
    M01639-1 100ug/vial
    EUR 476.4
    Description: Rabbit Monoclonal Cytokeratin 1 Antibody. Validated in WB and tested in Human, Mouse, Rat.

    Polyclonal TIMD4 / TIM4 / TIM-4 Antibody (C-Terminus)
    APR02278G 0.05mg
    EUR 580.8
    Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human TIMD4 / TIM4 / TIM-4 (C-Terminus). This antibody is tested and proven to work in the following applications:

    TIM-3 Peptide
    46-495P 0.1 mg
    EUR 405.6
    Description: TIM3 / HAVCR2 Peptide

    TIM-50 Peptide
    46-496P 0.1 mg
    EUR 405.6
    Description: TIM50 Peptide

    TIM-4 Peptide
    3813P 0.05 mg
    EUR 197.7
    Description: (CT) TIM-4 peptide

    TIM-4 Peptide
    3815P 0.05 mg
    EUR 197.7
    Description: (IN) TIM-4 peptide

    TIM-3 (Mouse), Fc-Fusion (Human)-Avi-Tag, Biotin-Labeled HiP™
    77000-1 25 µg
    EUR 295
    Description: Mouse TIM-3, also known as T-cell immunoglobulin mucin receptor 3, T-cell membrane protein 3, TIMD-3, Hepatitis A virus cellular receptor 2, HAVCR-2, and KIM-3. GenBank Accession No. NM_032782, a.a. 22-191, expressed in a HEK293 cells expression system. This protein is fused at the C-terminus to the Fc region of human IgG1 and is enzymatically biotinylated using Avi-tag™ technology. MW = 47 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.

    Anti-Integrin beta 1 Rabbit Monoclonal Antibody
    M00772-1 100ug/vial
    EUR 476.4
    Description: Rabbit Monoclonal Integrin beta 1 Antibody. Validated in IHC, WB and tested in Human, Mouse, Rat.

    Anti-ARG1/Arginase 1 Rabbit Monoclonal Antibody
    M01106-1 100ug/vial
    EUR 476.4
    Description: Rabbit Monoclonal ARG1/Arginase 1 Antibody. Validated in IP, WB and tested in Human, Mouse, Rat.

    Anti-MLANA/Mart 1 Rabbit Monoclonal Antibody
    M02033-1 100ug/vial
    EUR 476.4
    Description: Rabbit Monoclonal MLANA/Mart 1 Antibody. Validated in IF, WB and tested in Human.

    Anti-DSG1/Desmoglein 1 Rabbit Monoclonal Antibody
    M02655-1 100ug/vial
    EUR 476.4
    Description: Rabbit Monoclonal DSG1/Desmoglein 1 Antibody. Validated in IF, IHC, ICC, WB and tested in Human, Mouse, Rat.

    Anti-HMGB1/Hmg 1 Rabbit Monoclonal Antibody
    M00066-1 100ug/vial
    EUR 476.4
    Description: Rabbit Monoclonal HMGB1/Hmg 1 Antibody. Validated in Flow Cytometry, IF, IHC, ICC, WB and tested in Human, Mouse, Rat.

    Anti-p27 KIP 1 Rabbit Monoclonal Antibody
    M00173-1 100ug/vial
    EUR 476.4
    Description: Anti-p27 KIP 1 Rabbit Monoclonal Antibody tested for Flow Cytometry, IP, IF, IHC, ICC, WB in Human, Rat

    Anti-MHC class 1 Rabbit Monoclonal Antibody
    M00194-1 100ug/vial
    EUR 476.4
    Description: Rabbit Monoclonal MHC class 1 Antibody. Validated in IP, IF, IHC, WB and tested in Human.

    T-Cell Immunoglobulin Mucin Receptor 1 (TIM-1) Antibody
    abx415204-05mg 0.5 mg
    EUR 994.8

    T-Cell Immunoglobulin Mucin Receptor 1 (TIM-1) Antibody
    abx415206-01mg 0.1 mg
    EUR 526.8

    T-Cell Immunoglobulin Mucin Receptor 1 (TIM-1) Antibody
    abx433377-200ul 200 ul
    EUR 460.8

    T-Cell Immunoglobulin Mucin Receptor 1 (TIM-1) Antibody
    abx411874-01mg 0.1 mg
    EUR 644.4

    Human Triosephosphate Isomerase (TIM) Antibody
    30187-05111 150 ug
    EUR 313.2

    Histone H3K4 Methylation Antibody Panel Pack
    C10005
    • EUR 754.26
    • EUR 470.80
    • 3 x 25 µg
    • 3 x 25 ul

    Histone H3K9 Methylation Antibody Panel Pack
    C10006
    • EUR 754.26
    • EUR 470.80
    • 3 x 25 µg
    • 3 x 25 ul

    Histone H3K27 Methylation Antibody Panel Pack
    C10007
    • EUR 754.26
    • EUR 470.80
    • 3 x 25 µg
    • 3 x 25 ul

    Histone H3K36 Methylation Antibody Panel Pack
    C10008
    • EUR 754.26
    • EUR 470.80
    • 3 x 25 µg
    • 3 x 25 ul

    Histone H3K79 Methylation Antibody Panel Pack
    C10009
    • EUR 754.26
    • EUR 470.80
    • 3 x 25 µg
    • 3 x 25 ul

    Histone H4K20 Methylation Antibody Panel Pack
    C10012
    • EUR 754.26
    • EUR 470.80
    • 3 x 25 µg
    • 3 x 25 ul

    Histone H4 Acetylation Antibody Panel Pack
    C10013
    • EUR 754.26
    • EUR 470.80
    • 4 x 25 µg
    • 4 x 25 ul

    Histone H3 Phosphorylation Antibody Panel Pack
    C10014
    • EUR 754.26
    • EUR 470.80
    • 3 x 25 µg
    • 3 x 25 ul

    Histone H3R2 Methylation Antibody Panel Pack
    C10015
    • EUR 754.26
    • EUR 470.80
    • 3 x 25 µg
    • 3 x 25 ul

    Histone H3R8 Methylation Antibody Panel Pack
    C10016
    • EUR 754.26
    • EUR 470.80
    • 3 x 25 µg
    • 3 x 25 ul

    Histone H3R17 Methylation Antibody Panel Pack
    C10017
    • EUR 754.26
    • EUR 470.80
    • 3 x 25 µg
    • 3 x 25 ul

    Histone H3R26 Methylation Antibody Panel Pack
    C10018
    • EUR 754.26
    • EUR 470.80
    • 3 x 25 µg
    • 3 x 25 ul

    Histone H4R3 Methylation Antibody Panel Pack
    C10019
    • EUR 754.26
    • EUR 470.80
    • 3 x 25 µg
    • 3 x 25 ul

    HRP-Goat Anti-Mouse Secondary Antibody
    A12003
    • EUR 232.26
    • EUR 117.70
    • 350 µg
    • 350 ug

    DNA Methylation Antibody Panel Pack I
    C20000
    • EUR 458.46
    • EUR 270.60
    • each
    • 2 x 25 ul

    Nori Equine TIM-1 ELISA Kit
    GR106515 96-well
    EUR 553.2

    Nori Human TIM-1 ELISA Kit
    GR111038 96-well
    EUR 553.2

    Nori Canine TIM-1 ELISA Kit
    GR115040 96-well
    EUR 553.2

    Histone H3 Acetylation Antibody Panel Pack I
    C10010
    • EUR 928.26
    • EUR 588.50
    • 4 x 25 µg
    • 4 x 25 ul

    Histone H3 Acetylation Antibody Panel Pack II
    C10011
    • EUR 928.26
    • EUR 588.50
    • 4 x 25 µg
    • 4 x 25 ul

    Goat Anti-Rat Secondary Antibody, Biotin Conjugated
    A12002
    • EUR 232.26
    • EUR 117.70
    • 350 µg
    • 350 ug

    Anti-BOB-1/OBF-1 Rabbit Monoclonal Antibody, Clone#RM378
    M04431-1 100uL
    EUR 462
    Description: Anti-BOB-1/OBF-1 Rabbit Monoclonal Antibody, Clone#RM378 tested in WB, IHC, reactive to Human

    Histone H3 Methylation Antibody Panel Pack I – Active Genes
    C10000
    • EUR 928.26
    • EUR 588.50
    • 4 x 25 µg
    • 4 x 25 ul

    Histone H3 Methylation Antibody Panel Pack I – Repression Genes
    C10001
    • EUR 928.26
    • EUR 588.50
    • 4 x 25 µg
    • 4 x 25 ul

    Histone H3 Methylation Antibody Panel Pack II – Active Genes
    C10002
    • EUR 754.26
    • EUR 470.80
    • 3 x 25 µg
    • 3 x 25 ul

    Histone H3 Methylation Antibody Panel Pack II – Repression Genes
    C10003
    • EUR 928.26
    • EUR 588.50
    • 4 x 25 µg
    • 4 x 25 ul

    Histone H3 Methylation Antibody Panel Pack III – Active Genes
    C10004
    • EUR 928.26
    • EUR 588.50
    • 4 x 25 µg
    • 4 x 25 ul

    Anti-SERPINA1/Alpha 1 Antitrypsin Rabbit Monoclonal Antibody
    M00720-1 100ug/vial
    EUR 476.4
    Description: Rabbit Monoclonal SERPINA1/Alpha 1 Antitrypsin Antibody. Validated in IP, IF, WB and tested in Human.

    Anti-GPX1/Glutathione Peroxidase 1 Rabbit Monoclonal Antibody
    M01019-1 100ug/vial
    EUR 476.4
    Description: Rabbit Monoclonal GPX1/Glutathione Peroxidase 1 Antibody. Validated in IP, WB and tested in Human, Mouse, Rat.

    Anti-BAG-1 Rabbit Monoclonal Antibody, Clone#RM356
    M02423-1 100uL
    EUR 462
    Description: Anti-BAG-1 Rabbit Monoclonal Antibody, Clone#RM356 tested in WB, IHC, reactive to Human

    Anti-AFP/Alpha 1 Fetoprotein Rabbit Monoclonal Antibody
    M00522-1 100ug/vial
    EUR 476.4
    Description: Rabbit Monoclonal AFP/Alpha 1 Fetoprotein Antibody. Validated in IP, IF, WB and tested in Human.

    T-Cell Immunoglobulin Mucin Receptor 1 (TIM-1) Antibody (FITC)
    abx415205-01mg 0.1 mg
    EUR 610.8

    T-Cell Immunoglobulin Mucin Receptor 1 (TIM-1) Antibody (RPE)
    abx415207-100tests 100 tests
    EUR 710.4

    Anti-Phospho-AMPK alpha 1 (S496) Rabbit Monoclonal Antibody
    P00994-1 100ug/vial
    EUR 476.4
    Description: Rabbit Monoclonal Phospho-AMPK alpha 1 (S496) Antibody. Validated in IP, IF, WB and tested in Human.

    Anti-TIM-3 Antibody, PE-Labeled
    71121-2 100 µg
    EUR 510
    Description: R-Phycoerythrin-labeled recombinant human Anti-TIM-3 antibody recognizing the TIM3 binding region. This antibody has not been tested for cross-reactivity with any other species.

    TIM-3 Recombinant Protein
    91-327 0.05 mg
    EUR 537.9
    Description: T-Cell Membrane Protein 3 (TIM3) is a single-pass type I membrane protein that belongs to the TIM family of immunoglobulin superfamily. TIM3 includes a signal sequence (aa 1-21), an extracellular region (aa 22-202) with one Ig-like V-type domain, a transmembrane segment (aa 203-223), and a cytoplasmic domain (aa 224 - 301). TIM3 regulates macrophage activation, inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. It may be also involved in T-cell homing and as a receptor for LGALS9.

    TIM-3 Recombinant Protein
    91-942 0.05 mg
    EUR 537.9
    Description: Hepatitis A virus cellular receptor 2（HAVCR2）is a single-pass type I membrane protein and it contains 1 Ig-like V-type (immunoglobulin-like) domain. The protein belongs to the immunoglobulin superfamily, and TIM family of proteins. The protein regulates macrophage activation. It inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. It may be also involved in T-cell homing and it is receptor for LGALS9. CD4 (MIM 186940)-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells and their associated cytokines are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. The 2 types of cells also cross-regulate the functions of the other. TIM3 is a Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice.

    TIM-3 Recombinant Protein
    92-552 0.05 mg
    EUR 487.5
    Description: T cell immunoglobulin and mucin domain-3 (TIM3), also called hepatitis A virus cellular receptor 2 (HAVCR2), is a transmembrane glycoprotein of the TIM family of immune regulating molecules and plays an important role in the Th1-mediated immune response. TIM3 is expressed on the Th1 cells, CD8 T-cells, monocytes, and dendritic cells, but not on Th2 cells. TIM3 expressed by monocytes and dendritic cells facilitates phagocytosis of apoptotic cells and up-regulates cross-presentation of apoptotic cell-associated antigens through interaction with phosphatidylserine. Engagement of TIM3 by its ligand galectin-9 induces a range of immunosuppressive functions which enhance immune tolerance and inhibit anti-tumor immunity. Stimulation of TIM3 with an agonistic antibody promotes inflammation through the activation of innate immune cells. TIM3 is also regarded as a potential target molecule for immunotherapy. TIM3 and programmed cell death 1 (PD-1) as two important coinhibitory regulators of T cell responses, have been implicated with the T-cell dysfunction or exhaustion associated with chronic HBV infection including HBV-related HCC.

    TIM-3 Recombinant Protein
    92-596 0.05 mg
    EUR 481.2
    Description: T cell immunoglobulin and mucin domain-3 (TIM3), also called hepatitis A virus cellular receptor 2 (HAVCR2), is a transmembrane glycoprotein of the TIM family of immune regulating molecules and plays an important role in the Th1-mediated immune response. TIM3 is expressed on the Th1 cells, CD8 T-cells, monocytes, and dendritic cells, but not on Th2 cells. TIM3 expressed by monocytes and dendritic cells facilitates phagocytosis of apoptotic cells and up-regulates cross-presentation of apoptotic cell-associated antigens through interaction with phosphatidylserine. Engagement of TIM3 by its ligand galectin-9 induces a range of immunosuppressive functions which enhance immune tolerance and inhibit anti-tumor immunity. Stimulation of TIM3 with an agonistic antibody promotes inflammation through the activation of innate immune cells. TIM3 is also regarded as a potential target molecule for immunotherapy. TIM3 and programmed cell death 1 (PD-1) as two important coinhibitory regulators of T cell responses, have been implicated with the T-cell dysfunction or exhaustion associated with chronic HBV infection including HBV-related HCC.

    TIM-3 Recombinant Protein
    92-646 0.05 mg
    EUR 481.2
    Description: T cell immunoglobulin and mucin domain-3 (TIM3), also called hepatitis A virus cellular receptor 2 (HAVCR2), is a transmembrane glycoprotein of the TIM family of immune regulating molecules and plays an important role in the Th1-mediated immune response. TIM3 is expressed on the Th1 cells, CD8 T-cells, monocytes, and dendritic cells, but not on Th2 cells. TIM3 expressed by monocytes and dendritic cells facilitates phagocytosis of apoptotic cells and up-regulates cross-presentation of apoptotic cell-associated antigens through interaction with phosphatidylserine. Engagement of TIM3 by its ligand galectin-9 induces a range of immunosuppressive functions which enhance immune tolerance and inhibit anti-tumor immunity. Stimulation of TIM3 with an agonistic antibody promotes inflammation through the activation of innate immune cells. TIM3 is also regarded as a potential target molecule for immunotherapy. TIM3 and programmed cell death 1 (PD-1) as two important coinhibitory regulators of T cell responses, have been implicated with the T-cell dysfunction or exhaustion associated with chronic HBV infection including HBV-related HCC.

    TIM-3 Recombinant Protein
    92-656 0.05 mg
    EUR 481.2
    Description: T cell immunoglobulin and mucin domain-3 (TIM3), also called hepatitis A virus cellular receptor 2 (HAVCR2), is a transmembrane glycoprotein of the TIM family of immune regulating molecules and plays an important role in the Th1-mediated immune response. TIM3 is expressed on the Th1 cells, CD8 T-cells, monocytes, and dendritic cells, but not on Th2 cells. TIM3 expressed by monocytes and dendritic cells facilitates phagocytosis of apoptotic cells and up-regulates cross-presentation of apoptotic cell-associated antigens through interaction with phosphatidylserine. Engagement of TIM3 by its ligand galectin-9 induces a range of immunosuppressive functions which enhance immune tolerance and inhibit anti-tumor immunity. Stimulation of TIM3 with an agonistic antibody promotes inflammation through the activation of innate immune cells. TIM3 is also regarded as a potential target molecule for immunotherapy. TIM3 and programmed cell death 1 (PD-1) as two important coinhibitory regulators of T cell responses, have been implicated with the T-cell dysfunction or exhaustion associated with chronic HBV infection including HBV-related HCC.

    TIM-3 Recombinant Protein
    96-813 0.1 mg
    EUR 682.8
    Description: Hepatitis A virus cellular receptor 2 is also known as HAVCR2, FLJ14428, KIM3, TIM3, TIMD3, is a member of the TIM family of immune regulating molecules with one Ig-like V-type domain and a Ser/Thr-rich mucin stalk. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells and their associated cytokines are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. The 2 types of cells also cross-regulate the functions of the other. HAVCR2 is a Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice. HAVCR2 regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. May be also involved in T-cell homing. Dysregulation of the HAVCR2-galectin-9 pathway could underlie chronic autoimmune disease states in human, such as multiple sclerosis.

    TIM-3 Recombinant Protein
    97-027 0.1 mg
    EUR 714.3
    Description: Hepatitis A virus cellular receptor 2 is also known as HAVCR2, FLJ14428,  KIM3, TIM3, TIMD3, is a member of the TIM family of immune regulating molecules with one Ig-like V-type domain and a Ser/Thr-rich mucin stalk. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells and their associated cytokines are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. The 2 types of cells also cross-regulate the functions of the other. HAVCR2 is a Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice. HAVCR2 regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. May be also involved in T-cell homing. Dysregulation of the HAVCR2-galectin-9 pathway could underlie chronic autoimmune disease states in human, such as multiple sclerosis.

    TIM-3 Recombinant Protein
    97-028 0.1 mg
    EUR 651.3
    Description: Hepatitis A virus cellular receptor 2 is also known as HAVCR2, FLJ14428,  KIM3, TIM3, TIMD3, is a member of the TIM family of immune regulating molecules with one Ig-like V-type domain and a Ser/Thr-rich mucin stalk. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells and their associated cytokines are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. The 2 types of cells also cross-regulate the functions of the other. HAVCR2 is a Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice. HAVCR2 regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. May be also involved in T-cell homing. Dysregulation of the HAVCR2-galectin-9 pathway could underlie chronic autoimmune disease states in human, such as multiple sclerosis.

    Tim-3 Recombinant Protein
    90-548 100 ug
    EUR 752.1
    Description: The TIM (T cell/transmembrane, immunoglobulin and mucin) family plays a critical role in regulating immune responses, including allergy, asthma, transplant tolerance, autoimmunity and the response to viral infections. The unique structure of TIM immunoglobulin variable region domains allows highly specific recognition of phosphatidylserine (PtdSer), exposed on the surface of apoptotic cells. Tim-3, a type I transmembrane protein, contains an immunoglobulin and a mucin-like domain in its extracellular portion and a tyrosine phosphorylation motif in its cytoplasmic portion. TIM-3 is preferentially expressed on Th1 and Tc1 cells, and generates an inhibitory signal resulting in apoptosis of Th1 and Tc1 cells. TIM-3 is also expressed on some dendritic cells and can mediate phagocytosis of apoptotic cells and cross-presentation of antigen. Tim-3 functions to inhibit aggressive Th1-mediated auto- and alloimmune responses. Tim-3 pathway blockade by administration of Tim-3:Fc fusion protein accelerated diabetes in nonobese diabetic mice, caused hyperproliferation of Th1 cells and Th1 cytokine release in an experimental autoimmune encephalomyelitis (EAE) model and prevented acquisition of transplantation tolerance induced by costimulation blockade.

    Tim-3 Recombinant Protein
    90-549 100 ug
    EUR 752.1
    Description: The TIM (T cell/transmembrane, immunoglobulin and mucin) family plays a critical role in regulating immune responses, including allergy, asthma, transplant tolerance, autoimmunity and the response to viral infections. The unique structure of TIM immunoglobulin variable region domains allows highly specific recognition of phosphatidylserine (PtdSer), exposed on the surface of apoptotic cells. Tim-3, a type I transmembrane protein, contains an immunoglobulin and a mucin-like domain in its extracellular portion and a tyrosine phosphorylation motif in its cytoplasmic portion. TIM-3 is preferentially expressed on Th1 and Tc1 cells, and generates an inhibitory signal resulting in apoptosis of Th1 and Tc1 cells. TIM-3 is also expressed on some dendritic cells and can mediate phagocytosis of apoptotic cells and cross-presentation of antigen. Tim-3 functions to inhibit aggressive Th1-mediated auto- and alloimmune responses. Tim-3 pathway blockade by administration of Tim-3:Fc fusion protein accelerates diabetes in nonobese diabetic mice, causes hyperproliferation of Th1 cells and Th1 cytokine release in an experimental autoimmune encephalomyelitis (EAE) model and prevents acquisition of transplantation tolerance induced by costimulation blockade.

    Tim-3 Recombinant Protein
    90-550 100 ug
    EUR 752.1
    Description: The TIM (T cell/transmembrane, immunoglobulin and mucin) family plays a critical role in regulating immune responses, including allergy, asthma, transplant tolerance, autoimmunity and the response to viral infections. The unique structure of TIM immunoglobulin variable region domains allows highly specific recognition of phosphatidylserine (PtdSer), exposed on the surface of apoptotic cells. Tim-3, a type I transmembrane protein, contains an immunoglobulin and a mucin-like domain in its extracellular portion and a tyrosine phosphorylation motif in its cytoplasmic portion. TIM-3 is preferentially expressed on Th1 and Tc1 cells, and generates an inhibitory signal resulting in apoptosis of Th1 and Tc1 cells. TIM-3 is also expressed on some dendritic cells and can mediate phagocytosis of apoptotic cells and cross-presentation of antigen. Tim-3 functions to inhibit aggressive Th1-mediated auto- and alloimmune responses. Tim-3 pathway blockade by administration of Tim-3:Fc fusion protein accelerates diabetes in nonobese diabetic mice, causes hyperproliferation of Th1 cells and Th1 cytokine release in an experimental autoimmune encephalomyelitis (EAE) model and prevents acquisition of transplantation tolerance induced by costimulation blockade.

    Tim-4 Recombinant Protein
    90-551 100 ug
    EUR 752.1
    Description: The TIM (T cell/transmembrane, immunoglobulin and mucin) family plays a critical role in regulating immune responses, including allergy, asthma, transplant tolerance, autoimmunity and the response to viral infections. The unique structure of TIM immunoglobulin variable region domains allows highly specific recognition of phosphatidylserine (PtdSer), exposed on the surface of apoptotic cells. TIM-4 (T cell; immunoglobulin; Mucin-4), also known as SMUCKLER, is a 60 kDa member of the TIM family of immune regulating proteins. TIM-4 is exclusively expressed on antigen-presenting cells, where it mediates phagocytosis of apoptotic cells and plays an important role in maintaining tolerance. TIM-4 binds specifically to TIM-1 which is also the cellular receptor for the hepatitis A virus, and has been implicated in the development of asthma. Among hematopoietic cells, TIM-1 is expressed on activated B and T cells, preferentially in the Th2 subset of CD4+ T cells. The interaction of TIM-4 with TIM-1 induces costimulatory and hyperproliferative signals in T cells.

    Tim-4 Recombinant Protein
    90-552 100 ug
    EUR 752.1
    Description: Mouse T cell immunoglobulin and mucin domain-containing protein 4, also known as T cell membrane protein 4, TIMD4 and TIM4 is a single-pass type I membrane protein which belongs to the immunoglobulin superfamily and TIM family. TIM4 contains one Ig-like V-type (immunoglobulin-like) domain. It is expressed on dendritic cells and macrophages. TIM4 plays an important role in the proliferation of T helper type 2 (Th2) cells. TIM4 is involved in regulating T cell proliferation and lymphotoxin signaling. It is a ligand for HAVCR1 / TIMD1. The expression of TIM4 in fibroblasts enhanced their ability to engulf apoptotic cells. TIM4 and TIM1 are phosphatidylserine receptors for the engulfment of apoptotic cells and may also be involved in intercellular signaling in which exosomes are involved. Modulation of TIM4 production in dendritic cells (DCs) represents a novel therapeutic approach for the treatment of peanut allergy.

    TIM-4, human recombinant
    P1108-10 each
    EUR 183.6

    TIM-4, human recombinant
    P1108-50 each
    EUR 561.6

    Tim-2, Mouse Recombinant
    P1356-10 each
    EUR 196.8

    TIM-1 Rabbit Polyclonal Antibody

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